Correspondingly, FYN is not identified as a lead candidate kinase in our analyses of PDCL5 cells; these cell lines already have functionally deficient TP53. In contrast, our analyses did identify FYN as a candidate kinase in PDCL15 cells which express wild-type, fully functional TP53. Perhaps FYN demonstrates increased enzymatic activity in this cell line in order to subvert AMPK-dependent p53 tumor suppressive activity. This evidence concerns the gene FYN and neoplasm.