Although the infiltration and activation of immune cells is a characteristic of chronic inflammation processes, such as atherosclerosis [59], the analyses of different molecular surrogates of macrophage infiltration, i.e., Adgre1 and Cd68, in the present study did not provide evidence suggesting the differential accumulation of macrophages in the aortas of ApoE-deficient mice. Here, ADGRE1 is linked to atherosclerosis.