Interestingly, in a recent study on the Behcet’s disease (BD) hypomethylation in the 5′UTR region (including cg03546163) of FKBP5 characterized cases was demonstrated and it was strongly associated with high gene expression, suggesting a possible role of DNA methylation in the pathogenesis [27]. The gene discussed is FKBP5; the disease is Behcet disease.