Combined with the lists of nine differentially expressed genes involved in cell cycle progression identified with IPA, we found a potential microRNA-mediated gene expression alteration in curcumin-treated IPF fibroblasts, namely, downregulated hsa-miR-6724-5p and upregulated KLF10. Using TargetScan, the prediction of KLF10 as a target of hsa-miR-6724-5p was confirmed (site type: 8mer; context++ score: −0.51; context++ score percentile: 99). Here, KLF10 is linked to idiopathic pulmonary fibrosis.