BRCA1 and neoplasm: Our study has several limitations: (a) germline mutation status of individuals whose tumor tissues tested positive for a BRCA1/2 mutation was unknown; thus, it is unclear if the mutations detected were of germline or somatic origin (albeit this does not affect eligibility for PARP inhibitors); (b) many cases were referred with only one submitted paraffin block available for histologic review, introducing a selection bias and limiting our assessment of BRCA mutation associated morphologic features.