To evaluate the expression profile of m6A readers in lung cancer, we analyzed known readers, including YTHDF1/2/3, YTHDC1/2, HNRNPA2B1, HNRNPC/G, eIF3A, FMR1 and IGF2BP1/2, in LUAD and lung squamous cell carcinoma (LUSC) via the GEPIA database. The gene discussed is YTHDF1; the disease is squamous cell lung carcinoma.