Likewise, an HCC‐specific ceRNA network was constructed by integrating the prior‐driven and data‐driven ceRNA network, and four HCC‐related lncRNA‐miRNA‐mRNA regulatory axes SNHG11/hsa‐miR‐199a‐5p/E2F3, CRNDE/hsa‐miR‐199a‐5p/E2F3, MYLK‐AS1/hsa‐miR‐195‐5p/CHEK1, and MYLK‐AS1/hsa‐miR‐195‐5p/RASGEF1B were identified. Here, E2F3 is linked to hepatocellular carcinoma.