As expected, correlations higher than expected under the condition of local independence (in our sample a value >0.16) were found for most of the item pairs within each subscale and none between different subscales; exhaustion: EX1-EX4, EX1-EX8, EX3-EX4, EX3-EX5, EX3-EX8, EX4-EX7, EX4-EX8, EX7-EX8; mental distance: MD1-MD3, MD1-MD4, MD1-MD5, MD2-MD3, MD2-MD4, MD3-MD4, MD4-MD5; cognitive impairment: all pairs; and emotional impairment: EI1-EI2, EI1-EI4, EI1-EI5, EI2-EI4, EI2-EI5, EI3-EI4, EI3-EI5, EI4-EI5. The gene discussed is LY86; the disease is Cognitive impairment.