Whereas Δ10 3′-UTR ZIKV or anti–PD-1 therapy individual treatments improved long-term survival rates in GL261 tumor–bearing mice from 0% to 32% (anti–PD-1 alone) and 33% (Δ10 3′-UTR ZIKV alone), combination therapy improved long-term survival to approximately 80% (Figure 5C). This evidence concerns the gene PDCD1 and neoplasm.