Apart from HLA genes having a role in host genetic susceptibility to DF and DHF, genetic polymorphisms in several non-HLA genes also play a role, which include Fcγ receptor II (FcγRII, CD32), Vitamin D receptor (VDR), Human Platelet Antigen (HPA), Transporter associated with Antigen Processing (TAP), and few cytokine polymorphisms. The gene discussed is VDR; the disease is dengue disease.