To further explore the relationship between CXXC4 and the survival cycle of GC, clinical studies were conducted to determine the relationship between CXXC4 and the prognosis of patients with GC, the findings of which showed that patients with lower levels of CXXC4 (n = 56) had inferior etiology-specific survival compared with those patients with higher expression of CXXC4 (n = 46) (Figure 1E, p < 0.05). Here, CXXC4 is linked to gastric cancer.