ATXN1 and cancer: Of the 45 OSCC samples, they found various types of regulation of circ_0008309, but a substantial number of samples showed downregulation, and further analysis revealed the sponging activity toward miR-136-5P and miR-382-5P, which showed interaction with ATXN1, which is involved in the Notch signaling pathway for migration of cells, but its expression varies accordingly to other types of cancer, and further analysis is needed to understand the function of ATXN1 as an oncogene or tumor suppressor.