Upregulated levels of miR-204-3p targeted the APC2 gene and resulted in increased β-catenin, phosphorylated (p-)AKT, and p-ERK1/2 expression, causing tumor progression, whereas overexpression of circPKD2 was demonstrated to reverse the inhibitory effects of miR-204-3p on the APC2 gene in OSCC, thus suppressing tumor progression.34 The gene discussed is APC2; the disease is neoplasm.