In GC, targeting miR-107 resulted in upregulated levels of brain-derived neurotrophic factor (BDNF), leading to migration and proliferation of GC cells,56 colorectal cancers by forming the circHIPK3/mir-637/STAT3 axis, resulting in reduced autophagic death in cells and increasing oxaliplatin (OXA) resistance,57 and bladder cancer (BC), where circHIPK3 regulation is downregulated in BC and forms an axis with miR-533, reducing aggressiveness and metastasis of BC.58 This evidence concerns the gene BDNF and breast cancer.