PMAIP1 and neoplasm: We found excellent correlation between the three saturation studies used as a base for the present study, i.e., those of Kato et al., Kotler et al., and Giacomelli et al. We showed that the yeast assay using the NOXA promoter was highly correlated with the two studies performed in mammalian cells, thus confirming the importance of this gene in the tumor suppression function of TP5328.