BLVRB and Anxiety: The behaviors suggest that the Flr protein disruption of glutamate synapses produces an anxiety, obsessive compulsive-like phenotype similar to those seen in mouse strains in which neuropsychiatric candidate genes have been mutated (Welch et al., 2007; McFarlane et al., 2008; Peñagarikano et al., 2011; Peça and Feng, 2012).