The only on-study pericarditis recurrence occurred in one patient enrolled in part 1 who had a mild episode in the base TP of 5 days’ duration (NRS pain increase from 0 to 2 and CRP of 0.10 mg/dL), which did not require an increase of concomitant therapy nor the addition of a new medication to treat pericarditis; this patient completed the EP without further event. This evidence concerns the gene CRP and pericarditis.