Longitudinal studies reporting an association between higher blood IL-6, CRP, erythrocyte sedimentation rate (ESR) in childhood/adolescence and increased risks of psychotic symptoms (Khandaker et al., 2014) or diagnosis of schizophrenia (Kappelmann et al., 2019; Metcalf et al., 2017) subsequently in adulthood indicate that inflammation may play a role in causing psychosis rather than simply being a consequence of illness. Here, CRP is linked to schizophrenia.