CDKN2A and brain neoplasm: By contrast, no brain tumor formation was observed in the lentivirus injection with YAP1-MAMLD1 (without additional Cdkn2a loss) (Fig. 5b), whereas small tumor or neoplastic lesions were detected upon additional co-injection of sgCdkn2a (Fig. 5b and Additional file 10: Fig. S5C).