ANKRD1 and polycystic ovary syndrome: Interestingly, while we did not detect changes in AR gene expression in the present cells, our transcriptome data identified ANKRD1, a transcriptional repressor of the androgen receptor (AR), to be significantly downregulated in newly-formed PCOS adipocytes at days 7 and 12 (Additional file 2: Supplemental Fig. 7C, right panel).