Importantly, ASCs from a subset of these normal-weight PCOS women showed enhanced lipid accumulation during adipogenesis in vitro in combination with overexpression of both PPARγ and CEBPα, (Additional file 1: Supplemental Fig. 1), as master regulator genes of adipogenesis required for adipocyte differentiation and maintenance [24, 26, 27], suggesting specific genetic/epigenetic ASC characteristics in these PCOS women that may contribute to overexpression of these critical adipogenic genes. This evidence concerns the gene PPARG and polycystic ovary syndrome.