PPARG and polycystic ovary syndrome: In fact, differential peaks overlapping key regulators of adipogenesis, PPARγ and C/EBPα [24], were identified at day 0 and day 12, respectively (Additional file 2: Supplemental Fig. 5), in addition to up-regulation of RNA levels at days 3–12 found in PCOS cells (Fig. 2a, b), indicating regulatory changes in PPARγ and C/EBPα genes to be reflected in both chromatin accessibility and transcript abundance.