Glycogen storage disease type II (GSDII) or Pompe Disease (PD) is a rare autosomal recessive metabolic disorder caused by a deficiency of lysosomal enzyme, acid α-glucosidase (GAA), leading to intracellular glycogen storage in many tissues, mainly in skeletal muscle, heart and liver [1]. The gene discussed is GAA; the disease is Glycogen storage disease due to acid maltase deficiency.