VEGFA and non-small cell lung carcinoma: Furthermore, Cox multivariate proportional hazard analysis revealed that high pT stage (hazard ratio 2.91 [95% CI 1.77–4.78], p < 0.001), high pN stage (hazard ratio 2.02 [95% CI 1.31–3.11], p = 0.002), high M2 ratio (hazard ratio 1.53 [95% CI 1.01–2.33], p = 0.046), and dual M2 ratiohigh and VEGF-Chigh expression (hazard ratio 2.01 [95% CI 1.28–3.16], p = 0.003) are independent prognosis factors for poor overall survival in NSCLC patients (Table 3).