To investigate whether M2 ratio and VEGF family members have a combined effect on NSCLC prognosis, patients were divided into 4 groups according to M2 ratio and VEGF-A expression: M2 ratiolowVEGF-Alow, M2 ratiolowVEGF-Ahigh, M2 ratiohighVEGF-Alow, and M2 ratiohighVEGF-Ahigh. This evidence concerns the gene VEGFA and non-small cell lung carcinoma.