Interestingly, this gene is closely related to the IFITM5 gene, which produces a protein of the interferon-inducible trans-membrane (IFITM) family and is known to cause OI type V (IFITM5, c.-14C > T) and VI (IFITM5, c.119C > T, p.(Ser40Trp)) [41–43]. This evidence concerns the gene IFITM5 and osteogenesis imperfecta type 5.