PTBP1 and hepatocellular carcinoma: Polypyrimidine tract-binding protein 1 (PTBP1) is highly expressed in hepatocellular carcinoma and promotes the translation of cyclin D3 (CCND3) via interacting with the 5′-untranslated region (5′-UTR) of its mRNA, thereby playing a role in the development of hepatocellular carcinoma [24].RBPs are capable of specifically binding to conserved 3′-UTR sequences in target mRNAs, thereby modulating their stability and subsequent translation [25, 26].