BACH1 and cancer: Aside from the mentioned mechanisms of NRF2 regulation, numerous proteins and molecules interact with either KEAP1 or NRF2 or even compete with NRF2, such as BTB and CNC homolog 1 (BACH1) [42], contributing to the highly complex regulation/activation of NRF2, the feature particularly accentuated in cancer (reviewed in [43,44,45,46,47]).