CCND3 and familial pancreatic carcinoma: Veschi et al. observed nelfinavir-mediated G1 arrest of pancreatic cancer cells in a cell type-specific manner; protein levels of cyclin D3 and B1 were downregulated in response to nelfinavir monotherapy in pancreatic cancer cells, and were further decreased when nitroxoline and erlotinib were added to the treatment [32].