As miRNAs can reflect a direct readout of transcription factor activity, we also surveyed ChIP-seq data to analyze DNA regions encoding miRNAs elevated in FSHD for binding by the NF-κB and AP-1 transcription factors activated by S100A8 (Figure 5d). The gene discussed is NFKB1; the disease is facioscapulohumeral muscular dystrophy.