As expected, several muscle pathology-associated miRNAs are dysregulated in FSHD patients: miR-486 is a defined myomiR, miR-29b up-regulation promotes muscle atrophy, miR-146b is dysregulated in dystrophinopathies and myositis, miR-329 counteracts muscle hypertrophy, and three others are known to be dysregulated in myotonic dystrophy, lamin A (LMNA) dystrophy, and/or FSHD (miR-34a, miR-140-3p, miR-100, and miR-454). This evidence concerns the gene LMNA and myositis disease.