In addition, pSS patients had higher levels of the proinflammatory cytokines IL-6 (199.78 ± 62.91 pg/mL pSS vs. 82.63 ± 18.86 pg/mL HC, p < 0.001), IL-17 (5.77 ± 1.79 pg/mL pSS vs. 1.96 ± 0.61 pg/mL HC, p < 0.001), IL-12 (65.38 ± 15.95 pg/mL pSS vs. 27.64 ± 10.47 pg/mL HC, p < 0.001), TNF-alpha (341.72 ± 52.75 pg/mL pSS vs. 147.48 ± 22.15 pg/mL HC, p < 0.001) than healthy controls. This evidence concerns the gene IL17A and peeling skin syndrome.