TP53 and breast cancer: The most frequent driver genes found mutated were: TP53, BRCA1, BRCA2, PIK3CA, and PTEN. This result is consistent with large genomic studies on BC, including TCGA [62], METABRIC [47], and MSK-IMPACT [63], and with other TNBC from us and others [14,50,64,65,66].