CDH1 and neoplasm: Concordantly, Xu and colleagues reported that 1,25(OH)2D3 and two of its analogues reduce the tumor load in the Apcmin/+ mouse model of intestinal tumorigenesis associated with an increase of E-cadherin protein and a decrease of nuclear β-catenin levels and of the expression of the Wnt target genes c-Myc and Tcf1 [87].