All these discrepancies between different groups’ results could be explained by the huge variety of GFAP isoforms, post-translational modifications [49], and functional and morphological differences of GFAP-positive cell populations [18], and all these factors must be better characterized in further research investigating GFAP’s potential as an astrocytoma diagnostic marker. The gene discussed is GFAP; the disease is astrocytoma (excluding glioblastoma).