The pathological hallmark for Parkinson’s disease and related synucleinopathies is the accumulation of the pre-synaptic protein α-synuclein (product of the SNCA gene) in Lewy body aggregates within the brain together with the degeneration of dopaminergic neurons within the substantia nigra compacta [1,2]. The gene discussed is SNCA; the disease is synucleinopathy.