The HS-mGPS was significantly associated with clinicopathological factors, such as age (p = 0.022), albumin (p < 0.001), CRP (p < 0.001), operative procedure (p = 0.007), tumor size (p < 0.001), tumor depth (p < 0.001), lymph node metastasis (p = 0.017), pTNM stage (p < 0.001), and postoperative complications (p < 0.001). This evidence concerns the gene ALB and metastatic malignant neoplasm in the lymph nodes.