As shown in Fig. 2, suppression of autophagic flux using pharmacological inhibitors or transfection of siRNA targeting LC3B impeded FAO induction by leptin in both MCF‐7 (Fig. 2D,F) and T47D (Fig. 2E) breast cancer cells, which are essentially similar to the effect on ATP production. Here, MAP1LC3B is linked to breast carcinoma.