Pooling all of the expression of the genes in the classifier, ACTB, BLM, BUB1B, CCR1, CKAP5, CLCA2, DDX39, DTX2, ERBB2, ESR1, MKI67, OBSL1, PGR, PHACTR2, PIM1, PTI1, RCHY1, RPLPO, SF3B5, STIL, TFRC, TPX2, and YWHAB indicates an increased likelihood of breast cancer [26–28]; however, membership in a prognostic gene list is not necessarily indicative of a gene’s importance in cancer pathology. The gene discussed is PHACTR2; the disease is cancer.