This result suggested that HSP90B1 is a potential target in anti-cancer treatment and that it will be necessary to design a more specific inhibitor to target HSP90B1. Other potential targets include individual HSPs such as DNAJB11, an HSP40 member that is positively associated with 8 cancer hallmarks, and HYOU1, a large HSP member that is associated with 5 cancer hallmarks. This evidence concerns the gene DNAJB1 and cancer.