Furthermore, qRT-PCR results showed that circ-ERBIN expressions were negatively correlated with the miR-125a-5p and miR-138-5p in CRC stable cell lines (Additional file 1: Figure S6B and S6C), samples from subcutaneous tumors from xenograft mouse models of CRC (Fig. 6b and Additional file 1: Figure S6D) and clinical CRC samples (Fig. 6c and d). Here, ERBIN is linked to colorectal carcinoma.