In 2015, Durst et al. reported for the first time that the involvement of the dachsous catherin‐related 1 (DCHS1) gene on chromosome 11 in the pathology of myxoid MVP, among which two missense mutations (p.R2513H and p.R2330C) have been identified (Durst et al., 2015). Here, DCHS1 is linked to familial mitral valve prolapse.