It is interesting that the expression of KIAA0125 was high in patients with RUNX1 mutation but modest in those with RUNX1/RUNX1T1 fusion consisting with the fact that AML patients with a RUNX1 mutation usually had poor outcomes while those with RUNX1/RUNX1T1 fusion had favorable prognosis. This evidence concerns the gene RUNX1 and acute myeloid leukemia.