We previously developed a 11-gene mRNA expression signature, including AIF1L, CXCR7, DNTT, GPR56, H1F0, IFITM3, KIAA0125, MX1, STAB1, TM4SF1, and TNS3, for prognostication in AML patients [21]. This evidence concerns the gene TM4SF1 and acute myeloid leukemia.