In patients with T2DM and HF, a relationship was found between galectin-3 and LVMM/body surface area (r = −0.58, p = 0.001), PIIINP, TIMP-1, and LV end-diastolic volume (r = −0.68 and p = 0.042 and r = 0.38 and p = 0.02, respectively). This evidence concerns the gene TIMP1 and type 2 diabetes mellitus.