There were positive associations between Nt-proBNP concentrations and LA volume index (r = 0.44; p = 0.003), galectin-3, and values of left ventricular myocardial mass/body surface area (LVM/BSA) (r = −0.58, p = 0.001), PIIINP and LV EDV (r = 0.38; p = 0.02), and negative association between TIMP-1 concentrations and LV EDV (r = −0.68; p = 0.042) in groups with HF. This evidence concerns the gene LGALS3 and hydrops fetalis.