Quercetin alleviated the PCOS by suppressing the levels of inflammatory cytokines (IL-1β, IL-6, and tumor necrosis factor α) [49], increasing the activity of antioxidant enzymes (superoxide dismutase, catalase, glutathione-S-transferase, and reduced glutathione) and improving granulosa cell apoptosis (upregulation of Bcl-2 and downregulation of Bax) [50]. Here, TNF is linked to polycystic ovary syndrome.