As shown in Figure 4, all the included genes in the black module were DEGs (26) (Figure 4(a)), while the magenta module (Figure 4(b)) had 1 DEL (SMCR5) and 20 DEGs; the yellow module (Figure 4(c)) had 4 DELs (KLF3-AS1, LINC00910, MAPKAPK5-AS1, and WWC2-AS2) and 45 DEGs, indicating the 160 interaction pairs of the magenta and yellow modules may be especially pivotal [such as LINC00910-thioredoxin interacting protein (TXNIP), KLF3-AS1-phospholipase C gamma 2 (PLCG2), MAPKAPK5-AS1-mitogen-activated protein kinase kinase kinase 14 (MAP3K14), and WWC2-AS2-TXNIP] for PCOS. The gene discussed is MAPKAPK5; the disease is polycystic ovary syndrome.