MTOR and Hepatic fibrosis: Among other enriched pathways, the mTOR pathway is involved in liver regeneration and autophagy functions (Fouraschen et al., 2013), and Sphingosine 1-Phosphate Signaling pathway in liver fibrosis through regulating pleiotropic cell responses to inflammation, such as cell survival, migration, and vascular permeability (González-Fernández et al., 2017).