VEGFA and age-related macular degeneration: Silk fibroin abilities as nanocarrier for anti-VEGF particles has been tested by encapsulating bovine serum albumin (BSA, macromolecular model with similar weight to the antibodies that are usually used in AMD) showing a prolonged retention compared to free BSA solution and better distribution in in vitro studies with ARPE-19 and in vivo studies in a rabbit model (Yang et al., 2019).