CD274 and non-small cell lung carcinoma: IL-10 secreted by TAMs promotes the expression of PD-L1 in NSCLC cells, while Bufei Decoction can reduce the expression of IL-10 and CD206 in TAMs and PD-L1 in NSCLC cells, delaying the progression of tumors in NSCLC (128), which also means Bufei Decoction reduces the proportion of M2 macrophages in TAMs in tumor tissues to delay tumor progression.