IL5 and peanut allergic reaction: Interestingly, allergen-specific IL-5+ TH2 cells were only found in allergic eosinophilic gastroenteritis patients, whereas peanut allergy was associated with a dominant IL-5- TH2 response, indicating that heterogeneity within TH2 responses may favor IgE-mediated or eosinophil-dominant gastrointestinal inflammation (29).