IGF2 and Menkes disease: Taken together, as demonstrated in Figure 9, our findings propose that as a critical oncomiRNA as we have previously suggested (Teng et al., 2015), miR-M2-5p may trigger the virally-induced MD lymphomagenesis through multiple strategies, including regulating the RBM24-mediated p63 overexpression and the MYOD1-mediated IGF2 and Caspase-3 signaling pathways.