TRIM2 and neoplasm: Additionally, the relative mRNA expression levels of hsa_circ_0002286, hsa_circ_0000512, hsa_circ_0003596, hsa_circ_0035436, hsa-mir-222-5p and TRIM2 were markedly different between tumor cell lines and 293T cell line (P <0.05) (Figure 11B).