SLC5A2 and chronic kidney disease: Together, the outcomes of these trials demonstrate how the benefits of SGLT2 inhibitors, used in combination with RAS inhibitors, span the renal risk continuum, from patients with mild/moderate CKD (as seen in the EMPA-REG OUTCOME, CANVAS program, and DECLARE-TIMI 58 trials) to those with moderate/severe CKD (as observed in CREDENCE and DAPA-CKD).