SLC5A2 and acute kidney injury: Similar to the results of CVD-REAL 3, compared with DPP-4 inhibitors, SGLT2 inhibitor therapy was associated with decreased risks of ≥ 30% reduction in eGFR (OR: 0.70; 95% CI 0.49, 1.00), AKI (OR: 0.47; 95% CI 0.27, 0.80), hospitalization (OR: 0.66; 95% CI 0.56, 0.78), and all-cause mortality (OR: 0.43; 95% CI 0.20, 0.95) [109].