In the interests of maximising the sample, our HDP variable included both gestational hypertension and PE, and our model discrimination for HDP was weaker than that reported for the sFlt-1:PlGF ratio for PE alone [24] and that observed for a model including first antenatal clinical characteristics and repeat antenatal blood pressure measurements for PE or gestational hypertension alone (AUC 0.77–0.88) [6]. The gene discussed is PGF; the disease is preeclampsia.