Remarkably, in our samples, according to TNM staging of CRC patients, higher expression of WNT4 was observed with advanced stages (III and IV) compared with earlier stages (I and II) (94.57 ± 11.61 vs. 66.35 ± 8.097; P = 0.0464), while CA199 and CEA were not (Table 1). This evidence concerns the gene WNT4 and colorectal carcinoma.