DNMT3B expression was not correlated with gender (P >0.9999), age (P = 0.6821), or tumor size (P=0.7055), but was correlated with tumor (T) stages (P=0.0187), node metastasis (P =0.0235), and the muscle-invasive stage (P =0.0449) (Table 1). This evidence concerns the gene DNMT3B and neoplasm.