IAPP and early-onset autosomal dominant Alzheimer disease: These approaches have been shown to restrict the self-assembly of a range of model amyloid peptides, including those derived from Aβ [30,[234], [235], [236]], tau (involved in Alzheimer's disease and other neurodegenerative disorders) [234], β2m [237], and islet amyloid polypeptide (IAPP; associated with type II diabetes) [238].